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Miracle?

German doctors are reporting that a bone-marrow transplant meant to treat leukemia has left an HIV-infected patient without any signs of the AIDS-causing virus. Physicians Gero Hütter and Thomas Schneider intentionally sought out a bone--marrow donor with a genetic mutation known to resist AIDS. Now, more than 20 months after the procedure, no observable traces of the leukemia or HIV remain.

But Hütter and Schneider are reluctant to declare their 42-year-old American miracle patient cured. HIV is notoriously tricky, often lurking in the body at undetectable levels. Cocktails of HIV-suppressing drugs have long achieved similar results but have never succeeded in completely removing the virus from the body. The doctors also stress that bone-marrow transplants are an unlikely candidate for standard HIV treatment given their high risk for complications or even death.

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November 29, 2008, Vol. 23, No. 24

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